© 2018 by Janelle E. Letzen, PhD

 
Sex Hormones and Addiction
Meet the Scientist
  • Link to post on Instagram

Hello everyone, my name is Jean Rivera (@thebrainscientist on Instagram), and I’m a graduate student in the Neuroscience program at Weill Cornell. You can read more about my background here.

Science Snack

Our lab is interested in identifying and characterizing the neural circuit mechanisms of addiction and comorbid anxiety and affective neuropsychiatric disorders.

To study this, we mainly focus on the role of sex hormones in:

 

1) the organization of behaviorally-relevant limbic circuits 

 

2) the activity of cell type- and projection-defined neuronal populations within these circuits

 

3) the receptor-specific signaling of neuropeptides and neurotransmitters at critical synaptic nodes.

 

Using a number of complementary molecular, physiological, and behavioral techniques, including neuronal tracing, in situ hybridization, immunohistochemistry, confocal

Sushi Science | Janelle Letzen | Addiction

microscopy, slice electrophysiology, and in vivo and ex vivo optogenetics and chemogenetics, we are able to analyze neural circuit mechanisms of addiction and mood disorders at the anatomical, molecular, cellular, synaptic, circuit, and behavioral levels.

References

[1] The Williams Hippocampus and Memory Lab (image replica)
[2] pleillab.org